Stephen J. Schueler, M.D.

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Von Willebrand's Disease Overview

What is von Willebrand's disease?
A person with von Willebrand's disease has an inherited disease that prevents the blood from clotting normally. Those with von Willebrand's disease have inadequate amounts of von Willebrand factor in the bloodstream. The Von Willebrand factor is necessary for tiny blood cells, called platelets, to form a blood clot. About 1 out 10,000 people in the US have Von Willebrand's disease.

What are the symptoms of von Willebrand's disease?
Symptoms of von Willebrand's disease may include heavy menstrual bleeding, bleeding gums, nosebleeds, easy bleeding after an injury, and excessive bruising.

How does the doctor treat von Willebrand's disease?
Treatment for von Willebrand's disease includes avoiding aspirin and nonsteroidal anti-inflammatory medications, intravenous medications, and platelet transfusions.

Continue to Von Willebrand's Disease Incidence

Last Updated: Feb 23, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Von Willebrand's Disease References
  1. Gupta PK, Kannan M, Saxena R. Carrier detection in severe von Willebrand's disease. Ann Hematol. 2004 Oct;83(10):625-7. [15316757]
  2. Ingerslev J, Hvitfeldt Poulsen L, Sorensen B. Current treatment of von Willebrand's disease. Hamostaseologie. 2004 Feb;24(1):56-64. [15029274]
  3. Kujovich JL. von Willebrand's disease and menorrhagia: prevalence, diagnosis, and management. Am J Hematol. 2005 Jul;79(3):220-8. [1598123]
  4. Schlammadinger A, Boda Z. Laboratory screening and diagnosis of von Willebrand's disease. Clin Lab. 2002;48(7-8):385-93. [12146572]
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