The evaluation of typhoid fever begins with a history and physical exam.

Physical findings in someone with typhoid fever include:

• Fever
• Constipation
• Abdominal tenderness
• Enlarged liver
• Enlarged spleen
• Rash:
• Rose colored spots that start on the trunk and spread to the arms and legs
• Unintentional weight loss

Tests are necessary to make the diagnosis of typhoid fever.

Tests that may be used to evaluate typhoid fever include:

• Complete blood count
• Salmonella titer
• Blood cultures
• Kidney profile
• Salmonella PCR