What is thrombotic thrombocytopenic purpura?
A person with thrombotic thrombocytopenic purpura has abnormal blood clots that form in the small blood vessels. The blood clots block the delivery of oxygen to tissues, which can result in damage to the brain and the kidneys. Thrombotic thrombocytopenic purpura also results in abnormally low numbers of platelets and red blood cells in the bloodstream. This leads to the formation of purpura, which are bruises under the skin. The most common causes of thrombotic thrombocytopenic purpura are cancer, infections, and a medication side effect.

What are the symptoms of thrombotic thrombocytopenic purpura?
Symptoms of thrombotic thrombocytopenic purpura include fever, pale skin, fatigue, and a rash that looks like bruises or broken blood vessels under the skin. Additional symptoms may include jaundice, nosebleeds, bleeding gums, headache, and joint pains.

How does the doctor treat thrombotic thrombocytopenic purpura?
Treatment for thrombotic thrombocytopenic purpura includes filtering the blood, called plasmapheresis. Additional treatment for thrombotic thrombocytopenic purpura may include medication, fresh frozen plasma, blood transfusion, and surgery to remove the spleen.