Stephen J. Schueler, M.D.

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Threatened Abortion Rh Factor

The determination of maternal Rh status is important in a woman with threatened miscarriage.

The Rh is a part of a person's blood type. Blood from the mother can get into the infant's bloodstream during an a miscarriage. If the mother has a Rh-negative blood type, she can form antibodies that destroy the blood cells of the fetus who has a Rh-positive blood type. The destruction of the infant's red blood cells can result in severe anemia, called erythroblastosis fetalis.

RhoGAM is a medication used to help prevent this problem. RhoGAM is an antibody that can prevent Rh-negative mothers from developing antibodies against fetal blood cells that are Rh positive. Rh-negative pregnant women with vaginal bleeding need an injection of RhoGAM to block the process.

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Last Updated: Jan 5, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Threatened Abortion References
  1. Szabo I, Szilagyi A. Management of threatened abortion. Early Pregnancy. 1996 Dec;2(4):233-40. [9363221]
  2. Weiss JL, Malone FD, Vidaver J, et al. Threatened abortion: A risk factor for poor pregnancy outcome, a population-based screening study. Am J Obstet Gynecol. 2004 Mar;190(3):745-50. [15042008]
  3. Yip SK, Sahota D, Cheung LP, Lam P, Haines CJ, Chung TK. Accuracy of clinical diagnostic methods of threatened abortion. Gynecol Obstet Invest. 2003;56(1):38-42. [12876423]
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