Stephen J. Schueler, M.D.

Overview Incidence Risk Factors Symptoms Evaluation Treatment questions for doctor specialist Home Care warning signs Prevention Outlook Complications Underlying Cause Transmission

Syphilis Symptoms

Symptoms of syphilis are separated into three stages.

Syphilis stage 1

  • Shortly after a infection, a skin ulcer, called a chancre, develops. The chancre is a painless, hard, red, ulcerated sore often seen on the male genitals.
  • Less commonly, the chancre can be seen on other parts of the body
  • Sometimes chancres develop on the tongue or inside the rectum:
  • In females, the chancre occurs on the cervix or inside the vagina:
  • In the first stage of the disease, the chancre usually heals without treatment in 1 to 5 weeks.

Syphilis stage 2
This phase occurs 2-6 weeks after the chancre has healed.

Symptoms of the second stage of syphilis include:

Syphilis stage 3
In this stage of the disease, multiple organs, including the brain, may be affected.

Symptoms of stage 3 syphilis may include:

Continue to Syphilis Evaluation

Last Updated: Jan 24, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
Copyright DSHI Systems, Inc. Powered by: FreeMD - Your Virtual Doctor

PubMed Syphilis References
  1. Brown DL, Frank JE.Diagnosis and management of syphilis. Am Fam Physician. 2003 Jul 15;68(2):283-90. [12892348]
  2. Chan EL, Kingston MA, Carlin EM. The laboratory diagnosis of gonorrhoea and syphilis infection. J Fam Plann Reprod Health Care. 2004 Apr;30(2):126-7. [15087003]
  3. Lambert NL, Fisher M, Imrie J, Watson R, Mercer CH, Parry JV, Phillips A, Iversen A, Perry N, Dean GL. Community based syphilis screening: feasibility, acceptability, and effectiveness in case finding. Sex Transm Infect. 2005 Jun;81(3):213-216. [15923287]
  4. Singh AE, Romanowski B.Syphilis: review with emphasis on clinical, epidemiologic, and some biologic features. Clin Microbiol Rev. 1999 Apr;12(2):187-209. [10194456]
  5. Zeltser R, Kurban AK. Syphilis. Clin Dermatol. 2004 Nov-Dec;22(6):461-8. [15596316]
FreeMD is provided for information purposes only and should not be used as a substitute for evaluation and treatment by a physician. Please review our terms of use.