Stephen J. Schueler, M.D.

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Squamous Cell Carcinoma Overview

What is squamous cell carcinoma?
A person with squamous cell carcinoma has abnormal cells in the skin that multiply out of control. These cells can form tumors and spread to other parts of the body. The cause of squamous cell carcinoma is unknown, but exposure to the sun and genetics play a role in determining risk. About 1 in 1,000 people develop squamous cell carcinoma each year in the US. Most people with squamous cell carcinoma are cured with treatment.

What are the symptoms of squamous cell carcinoma?
Symptoms of a squamous cell carcinoma include a red, firm, scaly skin lesion that has a crusty surface. The skin lesion may crack or bleed, and does not heal.

How does the doctor treat squamous cell carcinoma?
Treatment for a squamous cell carcinoma may include surgery, chemotherapy, or radiation therapy.

Continue to Squamous Cell Carcinoma Incidence

Last Updated: Feb 11, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Squamous Cell Carcinoma References
  1. Campbell FA, Gupta G. The management of non-melanoma skin cancer. Hosp Med. 2005 May;66(5):288-93. [15920859]
  2. Clayman GL, Lee JJ, Holsinger FC, et al. Mortality risk from squamous cell skin cancer. J Clin Oncol. 2005 Feb 1;23(4):759-65. [15681519]
  3. Einspahr JG, Bowden GT, Alberts DS. Skin cancer chemoprevention: strategies to save our skin. Recent Results Cancer Res. 2003;163:151-64; discussion 264-6. [12903851]
  4. Glass AG, Hoover RN. The emerging epidemic of melanoma and squamous cell skin cancer. JAMA. 1989 Oct 20;262(15):2097-100. [2795783]
  5. Yuspa SH. The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis. J Dermatol Sci. 1998 May;17(1):1-7. [9651822]
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