Stephen J. Schueler, M.D.

Overview Risk Factors Symptoms Treatment Complications Underlying Cause Anatomy

Splenomegaly Treatment

Treatment for splenomegaly depends on the underlying cause. Treatment may include antibiotics, medications that suppress the immune system, chemotherapy, or surgery to remove the spleen.

Treatment for splenomegaly may include:

  • Antibiotics to treat an underlying infection
  • Medications that suppress the immune system:
    • Used when a malfunctioning immune system is targeting healthy blood cells for destruction by the spleen
  • Chemotherapy:
    • Used to treat cancer of the blood cells, which are removed by the spleen
  • Splenectomy:
    • Surgery to remove the spleen
    • May be performed when the spleen is severely damaged from an injury
    • May be performed when the spleen is removing too many blood cells, causing anemia

Continue to Splenomegaly Complications

Last Updated: Jan 5, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Splenomegaly References
  1. Hilmes MA, Strouse PJ. The pediatric spleen. Semin Ultrasound CT MR. 2007 Feb;28(1):3-11. [17366703]
  2. Kinderknecht JJ. Infectious mononucleosis and the spleen. Curr Sports Med Rep. 2002 Apr;1(2):116-20. [12831720]
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