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Definition


Spherocytosis Definition
Common names:
  • Hereditary Spherocytosis
  • Spherocytosis
What is spherocytosis?
A person with spherocytosis has an inherited disease that results in abnormally shaped red blood cells. The red blood cells are round, rather than elliptical. The deformed red blood cells have a shorter lifespan than normal red blood cells. This leads to a shortage of red blood cells in the bloodstream, called hemolytic anemia. Images

What are the symptoms of spherocytosis?
Symptoms of spherocytosis are the same as those of hemolytic anemia. Initial symptoms of spherocytosis may include anorexia, weakness, fatigue, pale skin, headaches, dizziness, and faintness upon standing. Symptoms of worsening spherocytosis may include: chest pain, difficulty breathing with exertion, fainting, palpitations, jaundice, and brown urine. Images

How does the doctor treat spherocytosis?
Treatment for spherocytosis may include blood transfusions, iron supplements, vitamin B supplements, and surgery to remove the spleen.

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Last Updated: Jul 10, 2009  References
Authors: Stephen J. Schueler, MDJohn H. Beckett, MDD. Scott Gettings, MD
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