Stephen J. Schueler, M.D.

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Seminoma Underlying Cause

The cause of testicular cancer is unknown, but genetics may play a role in determining risk.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Cancer cells can develop from any cells inside the testicle. The cells can spread through the lymphatic system or the bloodstream.


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Last Updated: Aug 11, 2008 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Seminoma References
  1. Balk C, Witjes JA. Advances in the management of testicular cancer. Expert Rev Anticancer Ther. 2004 Aug;4(4):669-77. [15270670]
  2. Garner MJ, Turner MC, Ghadirian P, Krewski D. Epidemiology of testicular cancer: an overview. Int J Cancer. 2005 Sep 1;116(3):331-9. [15818625]
  3. Masters JR, Koberle B. Curing metastatic cancer: lessons from testicular germ-cell tumours. Nat Rev Cancer. 2003 Jul;3(7):517-25. [12835671]
  4. Shabbir M, Morgan RJ. Testicular cancer. J R Soc Health. 2004 Sep;124(5):217-8. [15493780]
  5. Wirehn AB, Tornberg S, Carstensen J. Serum cholesterol and testicular cancer incidence in 45,000 men followed for 25 years. Br J Cancer. 2005 May 9;92(9):1785-6. [15827555]
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