Reye's Syndrome Overview
What is Reye's syndrome?
A child with Reye's syndrome has damage to the brain and the liver. The cause of Reye's syndrome is unknown, but Reye's syndrome seems to occur only in a small number of children who take aspirin during a viral infection. Reye's syndrome is extremely rare in the US: only 2 cases occur per year.
What are the symptoms of Reye's syndrome?
Initial symptoms of Reye's syndrome include vomiting, right upper abdominal pain, fatigue, headache, neck pain, and excessive sleepiness. Symptoms of worsening Reye's syndrome include jaundice, confusion and seizures.
How does the doctor treat Reye's syndrome?
Treatment for Reye's syndrome includes intravenous fluids, oxygen therapy, and medications. Treatment for severe Reye's syndrome may include anticonvulsant medications, kidney dialysis, and a ventilator to support breathing.
Continue to Reye's Syndrome Incidence
- Belay ED, Bresee JS, Holman RC, Khan AS, Shahriari A, Schonberger LB. Reye's syndrome in the United States from 1981 through 1997. N Engl J Med. 1999 May 6;340(18):1377-82. 
- Bhutta AT, Van Savell H, Schexnayder SM. Reye's syndrome: down but not out. South Med J. 2003 Jan;96(1):43-5. 
- Hardie RM, Newton LH, Bruce JC, Glasgow JF, Mowat AP, Stephenson JB, Hall SM. The changing clinical pattern of Reye's syndrome 1982-1990. Arch Dis Child. 1996 May;74(5):400-5. 
- Orlowski JP. Whatever happened to Reye's syndrome? Did it ever really exist? Crit Care Med. 1999 Aug;27(8):1582-7.