Stephen J. Schueler, M.D.

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Pyriformis Syndrome Pain Control

Medications commonly used to control pain and inflammation in adults with piriformis syndrome include:

  • Acetaminophen decreases fever and pain, but does not help inflammation.
  • Adult dosing is 2 regular strength (325 mg) every 4 hours or 2 extra-strength (500 mg) every 6 hours.
  • Maximum dose is 4,000 mg per day.
  • Avoid this drug if you have alcoholism, liver disease or an allergy to the drug. See the package instructions.
  • Common brand names include Tylenol, Panadol, and many others.





NSAID Precautions

Continue to Pyriformis Syndrome Warning Signs

Last Updated: Dec 23, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Pyriformis Syndrome References
  1. Benzon HT, Katz JA, Benzon HA, Iqbal MS. Piriformis syndrome: anatomic considerations, a new injection technique, and a review of the literature. Anesthesiology. 2003 Jun;98(6):1442-8. [12766656]
  2. Fishman LM, Anderson C, Rosner B. BOTOX and physical therapy in the treatment of piriformis syndrome. Am J Phys Med Rehabil. 2002 Dec;81(12):936-42. [12447093]
  3. Lang AM. Botulinum toxin type B in piriformis syndrome. Am J Phys Med Rehabil. 2004 Mar;83(3):198-202. [15043354]
  4. Papadopoulos EC, Khan SN. Piriformis syndrome and low back pain: a new classification and review of the literature. Orthop Clin North Am. 2004 Jan;35(1):65-71. [15062719]
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