Stephen J. Schueler, M.D.

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Purpura Henoch-Schonlein Underlying Cause

The cause of Henoch-Schonlein is unknown. Henoch-Schonlein is a rare illness that occurs most often in children, following an upper respiratory infection. For some reason, the immune system, which normally fights infection, mistakenly attacks the lining of the small blood vessels. This results in inflammation of the small blood vessels in the skin, intestine, and kidneys.

Last Updated: Nov 6, 2008 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Purpura Henoch-Schonlein References
  1. Chang WL, Yang YH, Lin YT, Chiang BL. Gastrointestinal manifestations in Henoch-Schonlein purpura: a review of 261 patients. Acta Paediatr. 2004 Nov;93(11):1427-31. [15513566]
  2. Gedalia A. Henoch-Schonlein purpura. Curr Rheumatol Rep. 2004 Jun;6(3):195-202. [15134598]
  3. Kraft DM, Mckee D, Scott C. Henoch-Schonlein purpura: a review. Am Fam Physician. 1998 Aug;58(2):405-8, 411. [9713395]
  4. Saulsbury FT. Henoch-Schonlein purpura in children. Report of 100 patients and review of the literature. Medicine (Baltimore). 1999 Nov;78(6):395-409. [10575422]
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