Stephen J. Schueler, M.D.

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PUD Surgery

Surgery may be required for peptic ulcer disease in the following cases:

  • The ulcer forms a hole through the wall of the stomach or intestine
  • The ulcer causes bleeding
  • The ulcer obstructs the movement of food through the intestine

Surgery for peptic ulcer disease includes:
  • Gastrectomy:
    • Removal of a portion of the stomach
  • Vagotomy:
    • Cutting the nerves that supply the stomach
  • Pyloroplasty:
    • Surgery on the lower portion of the stomach, near the first part of the small intestine
    • Generally combined with vagotomy

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Last Updated: Dec 22, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed PUD References
  1. Bodger K, Daly MJ, Heatley RV. Clinical economics review: Helicobacter pylori-associated peptic ulcer disease. Aliment Pharmacol Ther. 1997 Apr;11(2):273-82. [9146763]
  2. Ford A, Delaney B, Forman D, Moayyedi P. Eradication therapy for peptic ulcer disease in Helicobacter pylori positive patients. Cochrane Database Syst Rev. 2004 Oct 18;(4):CD003840. [15495066]
  3. Ford AC, Delaney BC, Forman D, Moayyedi P. Eradication therapy in Helicobacter pylori positive peptic ulcer disease: systematic review and economic analysis. Am J Gastroenterol. 2004 Sep;99(9):1833-55. [15330927]
  4. Vakil N, Fennerty MB. Direct comparative trials of the efficacy of proton pump inhibitors in the management of gastro-oesophageal reflux disease and peptic ulcer disease. Aliment Pharmacol Ther. 2003 Sep 15;18(6):559-68. [12969082]
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