Chemotherapy is used for advanced, metastatic prostate cancer. It uses drugs to directly kill cancer cells. Some forms of chemotherapy can be administered orally, while others are only administered intravenously or by injection into muscle tissue. Chemotherapy is used in advanced prostate cancer, after hormonal therapy has failed.

The most commonly used chemotherapeutic agents used to fight prostate cancer include:

• Docetaxel (Taxotere)
• Estramustine (Emcyt)
• Mitoxantrone (Novantrone)
• Paclitaxel (Taxol)