Stephen J. Schueler, M.D.

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Primary Biliary Cirrhosis Underlying Cause

Primary biliary cirrhosis may be caused by an abnormal immune system, which normally fights infection. The immune system mistakenly attacks bile duct cells, causing inflammation. The cause of the abnormal immune system in primary biliary cirrhosis is unknown.

Conditions that may occur with primary biliary cirrhosis include:

Continue to Primary Biliary Cirrhosis Anatomy

Last Updated: Feb 9, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Primary Biliary Cirrhosis References
  1. Angulo P, Lindor KD. Management of primary biliary cirrhosis and autoimmune cholangitis. Clin Liver Dis. 1998 May;2(2):333-51, ix. [15560036]
  2. Gong Y, Gluud C. Colchicine for primary biliary cirrhosis: a Cochrane Hepato-Biliary Group systematic review of randomized clinical trials. Am J Gastroenterol. 2005 Aug;100(8):1876-85. [16086725]
  3. Jones DE, James OF, Bassendine MF. Primary biliary cirrhosis: clinical and associated autoimmune features and natural history. Clin Liver Dis. 1998 May;2(2):265-82, viii. [15560032]
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