Stephen J. Schueler, M.D.

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Primary Biliary Cirrhosis Overview

What is a primary biliary cirrhosis?
A person with primary biliary cirrhosis has inflammation of the bile ducts in the liver. The inflammation obstructs the flow of bile, which damages cells in the liver. The damage can result in liver failure and liver cancer. The cause of primary biliary cirrhosis is unknown. About 1 out of 100,000 people in the US develop primary biliary cirrhosis each year.

What are the symptoms of primary biliary cirrhosis?
Symptoms of primary biliary cirrhosis include weakness, fatigue, jaundice, itching, abdominal pain, abdominal swelling, weakness, and weight loss.

How does the doctor treat primary biliary cirrhosis?
Treatment for primary biliary cirrhosis may include medications, a liver disease diet, and vitamin supplements. Treatment for severe primary biliary cirrhosis may include a liver transplant.

Continue to Primary Biliary Cirrhosis Incidence

Last Updated: Feb 11, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Primary Biliary Cirrhosis References
  1. Angulo P, Lindor KD. Management of primary biliary cirrhosis and autoimmune cholangitis. Clin Liver Dis. 1998 May;2(2):333-51, ix. [15560036]
  2. Gong Y, Gluud C. Colchicine for primary biliary cirrhosis: a Cochrane Hepato-Biliary Group systematic review of randomized clinical trials. Am J Gastroenterol. 2005 Aug;100(8):1876-85. [16086725]
  3. Jones DE, James OF, Bassendine MF. Primary biliary cirrhosis: clinical and associated autoimmune features and natural history. Clin Liver Dis. 1998 May;2(2):265-82, viii. [15560032]
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