Pituitary Gland Underactive Underlying Cause
The pituitary gland produces hormones. These hormones stimulate other organs to function, or stimulate other organs to produce additional hormones. In a person with hypopituitarism, the pituitary does not make enough of one of the hormones.
Hypopituitarism results in a shortage in one of the following hormones:
- Adrenocorticotropic hormone:
- Follicle stimulating hormone (FSH):
- Stimulates the production of eggs in the ovary of a woman. In men, FSH stimulates the production of sperm.
- Growth hormone:
- Stimulates growth in children, and the production of muscle in adults.
- Luteinizing hormone:
- Stimulates the ovary to release the egg.
- Melanocyte stimulating hormone:
- Stimulates the production of colored pigment in the skin.
- Prepares the pregnant female's breasts for milk production.
- Thyroid stimulating hormone:
- Stimulates the thyroid gland to produce thyroid hormones.
The most common causes of hypopituitarism include:
Continue to Pituitary Gland Underactive Anatomy
- Dattani MT. Novel insights into the aetiology and pathogenesis of hypopituitarism. Horm Res. 2004;62 Suppl 3:1-13. 
- Smith JC. Hormone replacement therapy in hypopituitarism. Expert Opin Pharmacother. 2004 May;5(5):1023-31.