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Pick's Disease Evaluation
Tests are required to confirm the diagnosis of Pick's disease.
Tests in those with Pick's disease may include:
- CT scan of the brain
- MRI scan of the brain
- SPECT scan of the brain
- PET scanning of the brain:
- Can detect changes in brain metabolism and activity.
- Lumbar puncture
- Brain biopsy
Blood testing in Pick's disease may include:
- Amyloid beta 42
- Amyloid beta 42 is a protein that can be elevated in some individuals with early-onset Alzheimer's disease. Amyloid beta is formed after the sequential cleavage of amyloid precursor protein (APP). Autosomal dominant mutations in APP can cause a hereditary form of Alzheimer's disease.
- N-acetyl aspartate
- Serum thiamine level
- Serum folate level
- Thyroid profile
- Electrolyte profile
- Serum iron level
For more information:
Continue to Pick's Disease Treatment
PubMed Pick's Disease References
- Dickson DW. Neuropathology of Pick's disease. Neurology. 2001 Jun;56(11 Suppl 4):S16-20. 
- Nee LE, Tierney MC, Lippa CF. Genetic aspects of Alzheimer's disease, Pick's disease, and other dementias. Am J Alzheimers Dis Other Demen. 2004 Jul-Aug;19(4):219-25. 
- Rossor MN. Pick's disease: a clinical overview. Neurology. 2001 Jun;56(11 Suppl 4):S3-5.