Stephen J. Schueler, M.D.

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Peripheral Vascular Disease Underlying Cause

Symptoms of peripheral vascular disease occur when the diseased (partially blocked) arteries are unable to provide enough oxygen in order to meet demand. The tissue starts to malfunction (causing pain) when the supply of oxygen and nutrients do not meet demand. The nerve tissue and skin are affected most.

Peripheral vascular disease is most often caused by atherosclerosis.

Uncommon causes for peripheral vascular disease include:

Continue to Peripheral Vascular Disease Anatomy

Last Updated: Feb 9, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Peripheral Vascular Disease References
  1. Baumgartner I, Schainfeld R, Graziani L. Management of peripheral vascular disease. Annu Rev Med. 2005;56:249-72. [15660512]
  2. Burns DM. Epidemiology of smoking-induced cardiovascular disease. Prog Cardiovasc Dis. 2003 Jul-Aug;46(1):11-29. [12920698]
  3. Dillavou E, Kahn MB. Peripheral vascular disease. Diagnosing and treating the 3 most common peripheral vasculopathies. Geriatrics. 2003 Feb;58(2):37-42. [12596496]
  4. Fine JJ, Hall PA, Richardson JH. Predictive power of cardiovascular risk factors for detecting peripheral vascular disease. South Med J. 2004 Oct;97(10):951-4. [15558920]
  5. Standridge JB. Hypertension and atherosclerosis: clinical implications from the ALLHAT Trial. Curr Atheroscler Rep. 2005 Mar;7(2):132-9. [15727729]
  6. Sukhija R, Yalamanchili K, Aronow WS, Kakar P, Babu S. Clinical characteristics, risk factors, and medical treatment of 561 patients with peripheral arterial disease followed in an academic vascular surgery clinic. Cardiol Rev. 2005 Mar-Apr;13(2):108-10. [15705262]
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