Stephen J. Schueler, M.D.

Overview Symptoms

Pemphigoid Overview

What is pemphigoid?
A person with bullous pemphigoid has a skin disorder where one has large blisters on the skin. Pemphigoid is a chronic autoimmune disease that is relatively uncommon. It may be more common in those with psoriasis and lichen planus and may be triggered by ultraviolet radiation, x-ray therapy, and exposure to some drugs. Drugs that have been associated with bullous pemphigoid include furosemide, captopril, penicillamine, antibiotics, and ibuprofen, as well as other nonsteroidal anti-inflammatory agents.

What are the symptoms of pemphigoid?
The symptoms of pemphigoid include itching, rashes, mouth sores, bleeding gums, and blisters on the arms, legs or trunk. In some patients, blisters develop on the skin in areas where there was a persistent hive-like skin lesion. There are several forms of pemphigoid, each one having a characteristically different appearance and distribution on the body.

How does the doctor treat pemphigoid?
The treatment of pemphigoid includes oral anti-inflammatory medications. Some may benefit from corticosteroids. Other medications include tetracycline, clobetasol, azathioprine, and rituximab. Patients should be aware of possible food triggers for this condition.

Continue to Pemphigoid Symptoms

Last Updated: Sep 7, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Pemphigoid References
  1. 1: Patton T, Korman N. Role of methotrexate in the treatment of bullous pemphigoid in the elderly. Drugs Aging. 2008;25(8):623-9. [18665656]
  2. Patricio P, Ferreira C, Gomes MM, Filipe P. Autoimmune bullous dermatoses: a review. Ann N Y Acad Sci. 2009 Sep;1173:203-10. [19758152]
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