Pathologic Fracture Anatomy
To better understand pathologic bone fracture, it helps to understand the anatomy of the bony skeleton.
The bony skeleton is a living structure that supports the entire body. Bone made up of an outer shell of cortical, or very dense, bone that surrounds a honeycomb-like structure of softer (cancellous) bone. Bone mainly consists of protein and calcium. Without calcium, bone will become weak.
The human skeleton can be divided into two sections:
- Axial skeleton: a total of 80 bones including the skull, spine, and chest
- Appendicular skeleton: a total of 126 bones including the pelvic girdle, limbs, feet and hands
- Fayad LM, Kamel IR, Kawamoto S, Bluemke DA, Frassica FJ, Fishman EK. Distinguishing stress fractures from pathologic fractures: a multimodality approach. Skeletal Radiol. 2005 May;34(5):245-59. Epub 2005 Mar 15. 
- Jacofsky DJ, Haidukewych GJ. Management of pathologic fractures of the proximal femur: state of the art. J Orthop Trauma. 2004 Aug;18(7):459-69. 
- Verlaan L, van der Wal B, de Maat GJ, Walenkamp G, Nollen-Lopez L, van Ooij A. Primary hyperparathyroidism and pathological fractures: a review. Acta Orthop Belg. 2007 Jun;73(3):300-5.