Stephen J. Schueler, M.D.

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Osteogenic Sarcoma Underlying Cause

The cause for osteosarcoma is unknown, genetics may play a role in determining risk.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Osteogenic Sarcoma Anatomy

Last Updated: Dec 22, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Osteogenic Sarcoma References
  1. Bacci G, Lari S. Current treatment of high grade osteosarcoma of the extremity: review. J Chemother. 2001 Jun;13(3):235-43. [11450880]
  2. Hillmann A, Ozaki T, Winkelmann W. Familial occurrence of osteosarcoma. A case report and review of the literature. J Cancer Res Clin Oncol. 2000 Sep;126(9):497-502. [11003561]
  3. Nakajima H, Sim FH, Bond JR, Unni KK. Small cell osteosarcoma of bone. Review of 72 cases. Cancer. 1997 Jun 1;79(11):2095-106. [9179055]
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