Stephen J. Schueler, M.D.

Nasal Allergies Antihistamines

Antihistamines, such as diphenhydramine (Benadryl) or chlorpheniramine, help reduce swelling of the lining to the nose in a person with allergic rhinitis.

Diphenhydramine Dosing Chart

AgeDoseIntervalMax Daily Dose
2-5 years6.25 mg4-6 hours37.5 mg/day
6-11 years12.5-25 mg4-6 hours150 mg/day
12 and older25-50 mg4-6 hours300 mg/day

Chlorpheniramine Dosing Chart
AgeDoseIntervalMax Daily Dose
Under 6consult your physician
6-11 years2 mg4-6 hours12 mg/day
12 and up4 mg4-6 hours24 mg/day

Long-acting antihistamines tend to cause less drowsiness and can be taken less frequently. Some of these are available without a prescription.

Examples of long-acting antihistamines include:

Some allergic rhinitis medications combine decongestants with antihistamines:

Continue to Nasal Allergies Corticosteroids

Last Updated: Nov 10, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Nasal Allergies References
  1. Arshad SH. Primary prevention of asthma and allergy. J Allergy Clin Immunol. 2005 Jul;116(1):3-14. [15990764]
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  3. Meltzer EO, Szwarcberg J, Pill MW: Allergic rhinitis, asthma, and rhinosinusitis: diseases of the integrated airway. J Manag Care Pharm 2004 Jul-Aug; 10(4): 310-7. [15298529]
  4. Nielsen LP, Mygind N, Dahl R: Intranasal corticosteroids for allergic rhinitis: superior relief? Drugs 2001; 61(11): 1563-79. [11577794]
  5. Nimmagadda SR, Evans R 3rd: Allergy: etiology and epidemiology. Pediatr Rev 1999 Apr; 20(4): 111-5. [10208083]
  6. Veling MC, Trevino RJ: The treatment of allergic rhinitis with immunotherapy: a review of 1,000 cases. Ear Nose Throat J 2001 Aug; 80(8): 542-3. [11523472]
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