The treatment for multiple myeloma usually includes some combination of erythropoietin, corticosteroids, bisphosphonate medications, chemotherapy, and radiation therapy. A bone marrow transplant may be an option for some patients.
The treatment options for multiple myeloma include:
- Epoetin alfa, erythropoietin (Epogen, Procrit)
- To treat anemia from multiple myeloma
- Antinausea medications
- Bisphosphonate medications for multiple myeloma
- Narcotic pain medication:
- Multiple myeloma patients should be advised to avoid nonsteroidal anti-inflammatory medications, aspirin, and other medications that are metabolized by the kidney.
- Chemotherapy for multiple myeloma:
- The administration of medicines that kill cancer cells.
- Melphalan (Alkeran)
- Doxorubicin (Adriamycin, Rubex)
- Bortezomib (Velcade)
- Vincristine (Oncovin)
- Medications that suppress the immune system:
- Used to prevent bone complications of multiple myeloma, such as spinal cord compression, and pathologic fracture.
- Pamidronate (Aredia)
- Zoledronic acid (Zometa)
- Radiation therapy for multiple myeloma
- Exposing cancer cells to radiation can kill them.
- Bone marrow transplant for multiple myeloma:
- Does not cure multiple myeloma, but may be required after chemotherapy
Myeloma Questions For Doctor
The following are some important questions to ask before and after treatment for multiple myeloma.
Questions to ask before treatment:
- What are my treatment options?
- What are the risks associated with treatment?
- Do I need to stay in the hospital?
- How long will I be in the hospital?
- What are the complications I should watch for?
- How long will I be on medication?
- What are the potential side effects of my medication?
- Does my medication interact with nonprescription medicines or supplements?
- Should I take my medication with food?
Questions to ask after treatment:
- Do I need to change my diet?
- Are there any medications or supplements I should avoid?
- When can I resume my normal activities?
- When can I return to work?
- Do I need a special exercise program?
- What else can I do to reduce my risk for complications?
- Are my children at risk for this condition?
- How often will I need to see my doctor for checkups?
- What local support and other resources are available?
Continue to Myeloma Home Care
- Angtuaco EJ, Fassas AB, Walker R, Sethi R, Barlogie B. Multiple myeloma: clinical review and diagnostic imaging. Radiology. 2004 Apr;231(1):11-23. 
- Kumar A, Loughran T, Alsina M, Durie BG, Djulbegovic B. Management of multiple myeloma: a systematic review and critical appraisal of published studies. Lancet Oncol. 2003 May;4(5):293-304. 
- Lynch HT, Sanger WG, Pirruccello S, Quinn-Laquer B, Weisenburger DD. Familial multiple myeloma: a family study and review of the literature. J Natl Cancer Inst. 2001 Oct 3;93(19):1479-83.