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Definition


Myelodysplastic Syndrome Definition
Common names:
  • Myelodysplastic Syndrome
What is myelodysplastic syndrome?
Myelodysplastic syndrome is a term used to describe a group of closely-related diseases that affect the bone marrow. All of these diseases affect how blood cells are produced by the bone marrow. Myelodysplastic syndrome causes a decrease in the production of all blood cells in the bone marrow. It is considered to be a pre-cancerous condition because most people with myelodysplastic syndrome develop acute myeloid leukemia. Manifestations of myelodysplastic syndrome include anemia, repeated bacterial infections, and easy bleeding due to a coagulopathy. Images

What are the symptoms of myelodysplastic syndrome?
Common symptoms of myelodysplastic syndrome include bone pain, abdominal pain, easy bleeding, fatigue, pale skin, weakness or fatigue, and lymph gland swelling. Myelodysplastic syndrome also causes symptoms of coagulopathy and symptoms of anemia. Images

How does the doctor treat myelodysplastic syndrome?
Treatment for myelodysplastic syndrome depends on the underlying cell type. Treatment may include the administration of growth factors, which encourage red blood cell and white blood cell production. Growth factors include neupogen, sargramostim, and erythropoietin. Additional treatment for myelodysplastic syndrome includes chemotherapy, radiation therapy, pain medications, and bone marrow transplant. Images

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Last Updated: Jun 9, 2009  References
Authors: Stephen J. Schueler, MDJohn H. Beckett, MDD. Scott Gettings, MD
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