Stephen J. Schueler, M.D.

Muscular Dystrophy Duchenne's

Characteristics of Duchenne's muscular dystrophy:

  • Symptoms start after a child learns to walk.
  • Progressive muscle weakness:
    • Children usually require a wheelchair by age 12.
  • Weakness is most common in the legs and pelvis.
  • Muscle weakness also occurs in the arms, neck, and other areas.
  • Muscle enlargement occurs in the legs.
  • Scoliosis is prominent.
  • Disability progresses through childhood.
  • People with Duchenne's muscular dystrophy usually die between 12 and 20 years of age.

Continue to Muscular Dystrophy Facioscapulohumeral

Last Updated: Dec 21, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Muscular Dystrophy References
  1. Cossu G, Sampaolesi M. New therapies for muscular dystrophy: cautious optimism. Trends Mol Med. 2004 Oct;10(10):516-20. [15464452]
  2. Gregorevic P, Chamberlain JS. Gene therapy for muscular dystrophy - a review of promising progress. Expert Opin Biol Ther. 2003 Aug;3(5):803-14. [12880380]
  3. Leyten QH, Gabreels FJ, Renier WO, ter Laak HJ. Congenital muscular dystrophy: a review of the literature. Clin Neurol Neurosurg. 1996 Nov;98(4):267-80. [8930416]
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