Stephen J. Schueler, M.D.

Overview Symptoms

Mononeuritis Multiplex Overview

What is mononeuritis multiplex?
A person with mononeuritis multiplex has damage to individual nerves, located in more than one location. The nerve damage causes persistent deep, aching pain, as well as episodes of severe, stabbing pain. The most common location of nerve damage is in the hip and thigh, but the nerves in the upper extremities can be affected also. Severe damage to the nerves can interrupt signals that pass from the brain, to the muscles. The lack of muscle stimulation results in muscle weakness, muscle atrophy, and loss of reflexes. Causes of mononeuritis multiplex include diabetes or nerve injury.

What are the symptoms of mononeuritis multiplex?
Symptoms of mononeuritis multiplex include numbness and tingling, burning pain, and muscle weakness in locations affected by mononeuritis multiplex.

How does the doctor treat mononeuritis multiplex?
Treatment of mononeuritis multiplex includes blood sugar control for those with diabetes, pain medication, and anticonvulsant medications, such as gabapentin, carbamazepine. Most people recover after treatment with medication and physical therapy.

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Last Updated: Nov 29, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Mononeuritis Multiplex References
  1. Corbett CF. Practical management of patients with painful diabetic neuropathy. Diabetes Educ. 2005 Jul-Aug;31(4):523-4, 526-8. [16100329]
  2. Malik RA. Current and future strategies for the management of diabetic neuropathy. Treat Endocrinol. 2003;2(6):389-400. [15981943]
  3. Olson DE, Norris SL. Diabetes in older adults. Overview of AGS guidelines for the treatment of diabetes mellitus in geriatric populations. Geriatrics. 2004 Apr;59(4):18-24. [15086070]
  4. Sadosky A, McDermott AM, Brandenburg NA, Strauss M. A review of the epidemiology of painful diabetic peripheral neuropathy, postherpetic neuralgia, and less commonly studied neuropathic pain conditions. Pain Pract. 2008 Mar;8(1):45-56. [18211592]
  5. Sullivan KA, Feldman EL. New developments in diabetic neuropathy. Curr Opin Neurol. 2005 Oct;18(5):586-90. [16155445]
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