Stephen J. Schueler, M.D.

Overview Symptoms

Membranous Nephropathy Overview

Another name for Membranous Nephropathy is Membranous Glomerulonephritis.

What is membranous glomerulonephritis?
A person with membranous glomerulonephritis has inflammation and thickening of part of the kidney that is responsible for filtering waste form the bloodstream. Membranous glomerulonephritis is a common cause of nephrotic syndrome in adults. The underlying cause for membranous glomerulonephritis is not always clear, but causes include infection, cancer, drugs, and autoimmune diseases. Autoimmune causes include ankylosing spondylitis, dermatomyositis, Grave's disease, Hashimoto's thyroiditis, rheumatoid arthritis, and lupus. Infectious causes include hepatitis B hepatitis C, leprosy, malaria, and syphilis.

What are the symptoms of membranous glomerulonephritis?
The symptoms of membranous glomerulonephritis include leg swelling, arm swelling (bilateral), weight gain, increased urination at night, hypertension, fatigue, and foamy urine. Additional symptoms include malaise and a loss of appetite.

How does the doctor treat membranous glomerulonephritis?
Treatment for membranous glomerulonephritis includes diuretic medication, medications to control hypertension, and medications that suppress the immune system. A low salt and low protein diet may also be helpful.

Continue to Membranous Nephropathy Symptoms

Last Updated: Nov 16, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Membranous Nephropathy References
  1. Nasr SH, Said SM, Valeri AM, Stokes MB, Masani NN, D'Agati VD, Markowitz GS. Membranous glomerulonephritis with ANCA-associated necrotizing and crescentic glomerulonephritis. Clin J Am Soc Nephrol. 2009 Feb;4(2):299-308. Epub 2009 Jan 21. [19158367]
  2. Valentini RP, Mattoo TK, Kapur G, Imam A. Membranous glomerulonephritis: treatment response and outcome in children. Pediatr Nephrol. 2009 Feb;24(2):301-8. Epub 2008 Oct 10. [18846392]
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