Stephen J. Schueler, M.D.

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Malignant Neoplasm of the Ureter Underlying Cause

The cause of transitional cell carcinoma is unknown, but genetics may play a role in determining risk.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Transitional cell cancer develops from the cells that line the genitourinary system.


Continue to Malignant Neoplasm of the Ureter Anatomy

Last Updated: Jul 10, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Malignant Neoplasm of the Ureter References
  1. Johansson SL, Cohen SM: Epidemiology and etiology of bladder cancer. Semin Surg Oncol 1997 Sep-Oct; 13(5): 291-8. [9259084]
  2. Montironi R, Lopez-Beltran A. The 2004 WHO classification of bladder tumors: a summary and commentary. Int J Surg Pathol. 2005 Apr;13(2):143-53. [15864376]
  3. Rosenberg JE, Carroll PR, Small EJ. Update on chemotherapy for advanced bladder cancer. J Urol. 2005 Jul;174(1):14-20. [15947569]
  4. Warde P, Gospodarowicz MK: New approaches in the use of radiation therapy in the treatment of infiltrative transitional-cell cancer of the bladder. World J Urol 1997; 15(2): 125-33. [9144903]
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