The evaluation of malignant melanoma begins with a history and physical exam. Nevi, or moles, on the skin can develop into melanoma.

Physical findings in moles that may indicate malignant melanoma include:

• Irregular border
• Mixed color
• Irregular shape
• Rapid change in size or shape
• Rapid change in color, such as black
• Size larger than 6 mm (about the size of a pencil eraser)

A skin biopsy is required to confirm the diagnosis of malignant melanoma.

Tests that may be used to evaluate malignant melanoma include:

• Bone scan
• Chest x-ray
• CT scanning of the brain
• CT scanning of the abdomen
• CT scan of the chest