Stephen J. Schueler, M.D.

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Malaria Transmission

Facts about malaria:

  • Infection in humans starts after a bite from an infected Anopheles mosquito, which carries the malaria parasites.
  • The parasites are released into the bloodstream, where they infect red blood cells.
  • After the initial infection, malaria organisms multiply quickly within red blood cells.
  • Swollen red cells will release merozoites, which can then invade other red blood cells and repeat the process.
  • The illness may occur 3 days to months after the bite.
  • Rarely, malaria is spread by a blood transfusion, or from a mother to her fetus.

Last Updated: Mar 26, 2009 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Malaria References
  1. Kent DM, Mwamburi DM, Bennish ML, Kupelnick B, Ioannidis JP. Clinical trials in sub-Saharan Africa and established standards of care: a systematic review of HIV, tuberculosis, and malaria trials. JAMA. 2004 Jul 14;292(2):237-42. [15249573]
  2. Schlagenhauf P. Mefloquine for malaria chemoprophylaxis 1992-1998: a review. J Travel Med. 1999 Jun;6(2):122-33. [10381965]
  3. Stoppacher R, Adams SP. Malaria deaths in the United States: case report and review of deaths, 1979-1998. J Forensic Sci. 2003 Mar;48(2):404-8. [12665001]
  4. Trampuz A, Jereb M, Muzlovic I, Prabhu RM. Clinical review: Severe malaria. Crit Care. 2003 Aug;7(4):315-23. [12930555]
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