Stephen J. Schueler, M.D.

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Major Depressive Disorder Symptoms

Major depression is the most serious kind of depression. It is characterized by a constant depressed mood and loss of interest in all activities that lasts for at least two weeks.

Common symptoms of major depression include:

Additional symptoms of major depression include:

Continue to Major Depressive Disorder Treatment

Last Updated: Jan 24, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Major Depressive Disorder References
  1. Badamgarav E, Weingarten SR, Henning JM, Knight K, Hasselblad V, Gano A Jr, Ofman JJ. Effectiveness of disease management programs in depression: a systematic review. Am J Psychiatry. 2003 Dec;160(12):2080-90. [14638573]
  2. Bair MJ, Robinson RL, Katon W, Kroenke K. Depression and pain comorbidity: a literature review. Arch Intern Med. 2003 Nov 10;163(20):2433-45. [14609780]
  3. Barrett B, Byford S, Knapp M. Evidence of cost-effective treatments for depression: a systematic review. J Affect Disord. 2005 Jan;84(1):1-13. [15620380]
  4. Neumeyer-Gromen A, Lampert T, Stark K, Kallischnigg G. Disease management programs for depression: a systematic review and meta-analysis of randomized controlled trials. Med Care. 2004 Dec;42(12):1211-21. [15550801]
  5. Remick RA. Diagnosis and management of depression in primary care: a clinical update and review. CMAJ. 2002 Nov 26;167(11):1253-60. [1245108]
  6. Wulsin LR. Is depression a major risk factor for coronary disease? A systematic review of the epidemiologic evidence. Harv Rev Psychiatry. 2004 Mar-Apr;12(2):79-93. [15204803]
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