Stephen J. Schueler, M.D.

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Macroglobulinemia Evaluation

An evaluation of Waldenstrom's macroglobulinemia begins with a history and physical examination.

A history of easy bruising, symptoms of Raynaud's disease and neurologic symptoms may suggest this diagnosis. Physical findings may show bruising, enlarged liver and spleen, and other abnormalities.

Physical findings in someone with Waldenstrom's macroglobulinemia may include:

Tests are necessary to confirm the diagnosis of Waldenstrom's macroglobulinemia.

Tests that may be used to evaluate Waldenstrom's macroglobulinemia include:

Continue to Macroglobulinemia Treatment

Last Updated: Jan 7, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Macroglobulinemia References
  1. Bjorkholm M, Johansson E, Papamichael D, Celsing F, Matthews J, Lister TA, Rohatiner AZ. Patterns of clinical presentation, treatment, and outcome in patients with Waldenstrom's macroglobulinemia: a two-institution study. Semin Oncol. 2003 Apr;30(2):226-30. [12720141]
  2. Chen CI. Treatment for Waldenstrom's macroglobulinemia. Ann Oncol. 2004 Apr;15(4):550-8. [15033658]
  3. Dimopoulos MA, Anagnostopoulos A. Waldenstrom's macroglobulinemia. Best Pract Res Clin Haematol. 2005;18(4):747-65. [16026748]
  4. Dimopoulos MA, Kyle RA, Anagnostopoulos A, Treon SP. Diagnosis and management of Waldenstrom's macroglobulinemia. J Clin Oncol. 2005 Mar 1;23(7):1564-77. [15735132]
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