Stephen J. Schueler, M.D.

Lymphoma Hodgkin's Evaluation

The evaluation of Hodgkin's disease begins with a medical history and physical examination.

Physical findings in someone with Hodgkin's disease may include:


Testing is necessary to confirm the diagnosis of Hodgkin's disease.

Tests that may be used to evaluate Hodgkin's disease include:

Additional tests that may be used to evaluate Hodgkin's disease include:

Additional imaging tests that may be used to evaluate Hodgkin's disease include:

For more information:

Lymphoma Hodgkin's Staging

In order to determine the best treatment, doctors need to know the stage of the lymphoma.

In order to stage lymphoma, two variables are determined:

  • The type of cells that are multiplying in the lymph nodes
  • Whether the lymphoma has spread to other lymph nodes or other organs

Most people with lymphoma are staged using the Ann Arbor system. This includes stages 1-4 (I-IV), along with certain letters that represent other factors.

The letter system includes:
  • A: no symptoms
  • B: symptoms of fever, night sweats or weight loss
  • E:spread to one site nearby, but outside of affected lymph nodes
  • X: bulky disease larger than 10 cm

Stage 1
In stage 1 (I), the lymphoma is present only in a single site, such as a lymph node.
Stage 2
In stage 2 (II), the lymphoma is present in 2 or more lymph nodes on the same side of the diaphragm, or in a single organ outside of the lymph nodes.
Stage 3
In stage 3 (III), the lymphoma is present on both sides of the diaphragm, with or without involvement of the spleen or other organs.
Stage 4
In stage 4 (IV), the lymphoma is present in multiple organs.

Lymphoma Hodgkin's Stage 1

In stage 1 Hodgkin's disease, the lymphoma is present only in a single site, such as a lymph node.

Lymphoma Hodgkin's Stage 2

In stage 2 Hodgkin's disease, the lymphoma is present:

  • In 2 or more lymph nodes on the same side of the diaphragm, or
  • In a single organ outside of the lymphatic system

Lymphoma Hodgkin's Stage 3

In stage 3 Hodgkin's disease, the lymphoma is present on both sides of the diaphragm.

Lymphoma Hodgkin's Stage 4

In stage 4 Hodgkin's disease, the lymphoma is present in multiple areas of the body.

Continue to Lymphoma Hodgkin's Treatment

Last Updated: Dec 15, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Lymphoma Hodgkin's References
  1. Cartwright RA, Watkins G. Epidemiology of Hodgkin's disease: a review. Hematol Oncol. 2004 Mar;22(1):11-26. [15152367]
  2. Dieckmann K, Potter R, Wagner W, Prott FJ, Hornig-Franz I, Rath B, Schellong G. Up-front centralized data review and individualized treatment proposals in a multicenter pediatric Hodgkin's disease trial with 71 participating hospitals: the experience of the German-Austrian pediatric multicenter trial DAL-HD-90. Radiother Oncol. 2002 Feb;62(2):191-200. [11937246]
  3. McCunney RJ. Hodgkin's disease, work, and the environment. A review. J Occup Environ Med. 1999 Jan;41(1):36-46. [9924719]
  4. Provencio M, Espana P, Millan I, Yebra M, Sanchez AC, de la Torre A, Bonilla F, Regueiro CA, de Letona JM. Prognostic factors in Hodgkin's disease. Leuk Lymphoma. 2004 Jun;45(6):1133-9. [15359992]
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