Stephen J. Schueler, M.D.

Lymphocytic Leukemia Chronic Evaluation

The evaluation of chronic lymphocytic leukemia begins with a medical history and physical examination.

Physical findings in those with chronic lymphocytic leukemia may include:


Testing is always needed to diagnose and monitor chronic lymphocytic leukemia.

Tests that may be used to evaluate chronic lymphocytic leukemia include:

Imaging tests for chronic lymphocytic leukemia may include:

Lymphocytic Leukemia Chronic Similar Conditions

Conditions that cause symptoms similar to chronic lymphocytic leukemia include:

Lymphocytic Leukemia Chronic Stage

There are two methods used to group patients into various degrees of severity.

These are the:

  • Rai system
  • Binet classification

Lymphocytic Leukemia Chronic Binet Class

Binet Classification

  • Clinical Stage A: normal red blood cell and platelet counts; less than 3 areas of lymph nodes involved
  • Clinical Stage B: normal red blood cell and platelet counts; more than 3 areas of lymph nodes involved
  • Clinical Stage C: presence of anemia and/or low platelet counts with multiple areas of lymph nodes involved

Lymphocytic Leukemia Chronic Rai Class

Rai stages for chronic lymphocytic leukemia:

  • Stage 0: low risk patients with lymphocyte count more than 15,000
  • Stage 1: intermediate risk patients with elevated lymphocyte count and enlarged lymph nodes
  • Stage 2: high risk patients with elevated lymphocyte count, with possibly enlarged lymph nodes, liver or spleen
  • Stage 3: high risk patients with elevated lymphocyte count, plus anemia and possibly enlarged lymph nodes, liver or spleen
  • Stage 4: high risk patients with elevated lymphocyte count and low platelet count

Continue to Lymphocytic Leukemia Chronic Treatment

Last Updated: Dec 7, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Lymphocytic Leukemia Chronic References
  1. Yee KW, O'Brien SM. Chronic lymphocytic leukemia: diagnosis and treatment. Mayo Clin Proc. 2006 Aug;81(8):1105-29. [16901035]
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