Lip Swelling Evaluation
- Enlarged lips
- Cold sore
Testing may be necessary to detect hereditary angioedema as a cause of lip swelling.
Tests that may be used to evaluate lip swelling include:
- Complete blood count
- C1 esterase blood level:
- An important test for anyone who may have hereditary angioedema. Low levels of this enzyme will confirm this diagnosis.
- Allergy testing may include one or more of the following:
- Aquagenic: a test used to detect water-induced urticaria.
- Delayed Pressure: this test involves the placement of a 5 to 10 pound object on the skin for 10 to 15 minutes and then observing the skin's reaction for the next three hours.
- Dermatographism: a test involving the skin's reaction upon being scratched by a tongue blade; the course of the tongue blade is seen in a welt-like pattern on the skin
- Ice Cube Test: touching ice to the skin can trigger cold-induced urticaria in some individuals.
- Methacholine Test: this is a test that is used to identify cholinergic or exercise-induced urticaria.
- Skin testing: the most common test where small amounts of allergens are placed into the skin.
For more information:
Continue to Lip Swelling Treatment
PubMed Lip Swelling References
- Cohen EG, Soliman AM. Changing trends in angioedema. Ann Otol Rhinol Laryngol. 2001 Aug;110(8):701-6. 
- Khanna G, Sato Y, Smith RJ, Bauman NM, Nerad J. Causes of facial swelling in pediatric patients: correlation of clinical and radiologic findings. Radiographics. 2006 Jan-Feb;26(1):157-71. 
- O'Brien JG, Chennubhotla SA, Chennubhotla RV. Treatment of edema. Am Fam Physician. 2005 Jun 1;71(11):2111-7.