Stephen J. Schueler, M.D.

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Leukemia Acute Lymphocytic Underlying Cause

The cause of acute lymphocytic leukemia is unknown, but genetics may play a role.

Genes control the functions inside a cell. Special genes control how cells divide and grow. Cancer occurs when the damaged genes stimulate the cell to multiply out of control. The exact cause for this damage is unknown.


  • DNA
  • Genes on chromosomes
  • Cancer cells
  • Cancer cell division

Continue to Leukemia Acute Lymphocytic Anatomy

Last Updated: Nov 9, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Leukemia Acute Lymphocytic References
  1. Alderton LE, Spector LG, et al. Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: a report from the Children's Oncology Group. Am J Epidemiol. 2006 Aug 1;164(3):212-21. [16760223]
  2. Fulcher JW, Allred TJ, et al. Granular acute lymphoblastic leukemia in adults: report of a case and review of the literature. South Med J. 2006 Aug;99(8):894-7. [16929890]
  3. Haferlach T, Kern W, Schnittger S, Schoch C. Modern diagnostics in acute leukemias. Crit Rev Oncol Hematol. 2005 Nov;56(2):223-34. [16213152]
  4. Pui CH, Pei D, Sandlund JT, et al. Risk of adverse events after completion of therapy for childhood acute lymphoblastic leukemia. J Clin Oncol. 2005 Nov 1;23(31):7936-41. [16258093]
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