Stephen J. Schueler, M.D.

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Kawasaki Disease Underlying Cause

The cause of Kawasaki disease is unknown. Most experts believe that Kawasaki disease may be caused by a malfunctioning immune system, which normally fights infection. The immune system may mistakenly attack normal tissue, causing inflammation and irritation.

Last Updated: May 22, 2008 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Kawasaki Disease References
  1. Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, Shulman ST, Bolger AF, Ferrieri P, Baltimore RS, Wilson WR, Baddour LM, Levison ME, Pallasch TJ, Falace DA, Taubert KA; Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics. 2004 Dec;114(6):1708-33. [15574639]
  2. Royle J, Burgner D, Curtis N. The diagnosis and management of Kawasaki disease. J Paediatr Child Health. 2005 Mar;41(3):87-93. [15790316]
  3. Wong D, Harder J, Jadavji T. Kawasaki disease, myocardial infarction and coronary artery revascularization. Can J Cardiol. 2005 May 15;21(7):601-4. [15940359]
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