Stephen J. Schueler, M.D.

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Jakob-Creutzfeldt Disease Evaluation

The evaluation of Creutzfeldt-Jakob disease begins with a history and physical exam.

The physical exam in those with Creutzfeldt-Jakob disease is usually normal.

Evaluation of Creutzfeldt-Jakob disease includes:

  • Neurological evaluation
  • Psychiatric evaluation

There is no single test for diagnosing this condition. Creutzfeldt-Jakob disease must be confirmed with brain biopsy, usually on autopsy.

Tests that may be used to evaluate Creutzfeldt-Jakob disease include:

Blood tests that may be used to evaluate Creutzfeldt-Jakob disease include:

For more information:

Continue to Jakob-Creutzfeldt Disease Treatment

Last Updated: Dec 8, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Jakob-Creutzfeldt Disease References
  1. Beghi E, Gandolfo C, Ferrarese C, Rizzuto N, Poli G, Tonini MC, Vita G, Leone M, Logroscino G, Granieri E, Salemi G, Savettieri G, Frattola L, Ru G, Mancardi GL, Messina C. Bovine spongiform encephalopathy and Creutzfeldt-Jakob disease: facts and uncertainties underlying the causal link between animal and human diseases. Neurol Sci. 2004 Jul;25(3):122-9. [15300459]
  2. Glatzel M, Stoeck K, Seeger H, Luhrs T, Aguzzi A. Human prion diseases: molecular and clinical aspects. Arch Neurol. 2005 Apr;62(4):545-52. [15824251]
  3. Mallucci G, Collinge J. Update on Creutzfeldt-Jakob disease. Curr Opin Neurol. 2004 Dec;17(6):641-7. [15542971]
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