Stephen J. Schueler, M.D.


Insulin Resistance Syndrome Overview

Another name for Insulin Resistance Syndrome is Metabolic Syndrome.

What is metabolic syndrome?
A person with metabolic syndrome has a group of conditions that, together, increase the risk for diabetes, heart disease, and stroke. Conditions include high triglyceride levels, high cholesterol levels, high blood sugar levels, obesity around the waist, and high blood pressure. The more conditions a person has, the greater the risk. Metabolic syndrome may be caused by insulin resistance, in which cells in the body do not respond to insulin properly. Insulin is a hormone that reduces blood sugar (glucose) levels by stimulating the body to utilize glucose for energy. About 25 percent of the population of the US has metabolic syndrome.

What are the criteria for metabolic syndrome?
In order to have metabolic syndrome, a person must have more than two of the following:

How does the doctor treat metabolic syndrome?
Treatment for metabolic syndrome depends on which conditions a person has. Treatment for metabolic syndrome may include medications and changes in life style, such as an increase in exercise, a low-fat diet, a low cholesterol diet, weight loss, and stopping smoking.

Last Updated: Aug 27, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Insulin Resistance Syndrome References
  1. Denys K, Cankurtaran M, Janssens W, Petrovic M. Metabolic syndrome in the elderly: an overview of the evidence. Acta Clin Belg. 2009 Jan-Feb;64(1):23-34. Review. [19317238]
  2. Jiamsripong P, Mookadam M, Alharthi MS, Khandheria BK, Mookadam F. The metabolic syndrome and cardiovascular disease: part 2. Prev Cardiol. 2008 Fall;11(4):223-9. Review. [19476575]
  3. Malik S, Wong ND. Metabolic syndrome, cardiovascular risk and screening for subclinical atherosclerosis. Expert Rev Cardiovasc Ther. 2009 Mar;7(3):273-80. Review. [19296765]
  4. Natali A, Pucci G, Boldrini B, Schillaci G. Metabolic syndrome: at the crossroads of cardiorenal risk. J Nephrol. 2009 Jan-Feb;22(1):29-38. Review. [19229816]
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