Stephen J. Schueler, M.D.

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Inappropriate ADH Syndrome Treatment

The emergency treatment of acute or severe hyponatremia (low sodium in the bloodstream) due to the syndrome of inappropriate antidiuretic hormone (SIADH) includes the administration of saline solution. The replacement of sodium must not be delivered too aggressively, or it could trigger central pontine myelinolysis.

Long term treatment for the syndrome of inappropriate antidiuretic hormone (SIADH) may include reducing the amount of water in the diet, diuretic medications, and medications that stimulate the excretion of water from the kidneys.

General treatment for the syndrome of inappropriate antidiuretic hormone (SIADH) may include:

  • Water restriction for SIADH
  • High sodium and high protein diet

Medications used to treat the syndrome of inappropriate antidiuretic hormone (SIADH) may include:

Inappropriate ADH Syndrome Specialist

Physicians from the following specialties evaluate and treat the syndrome of inappropriate antidiuretic hormone:

Continue to Inappropriate ADH Syndrome Home Care

Last Updated: Jun 13, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Inappropriate ADH Syndrome References
  1. Anpalahan M.Chronic idiopathic hyponatremia in older people due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) possibly related to aging. J Am Geriatr Soc. 2001 Jun;49(6):788-92. [11454119]
  2. Kanda M, Omori Y, Shinoda S, Yamauchi T, Tamemoto H, Kawakami M, Ishikawa SE. SIADH closely associated with non-functioning pituitary adenoma. Endocr J. 2004 Aug;51(4):435-8. [15351800]
  3. Musch W, Decaux G. Treating the syndrome of inappropriate ADH secretion with isotonic saline. QJM. 1998 Nov;91(11):749-53. [10024938]
  4. Musch W, Hedeshi A, Decaux G. Low sodium excretion in SIADH patients with low diuresis. Nephron Physiol. 2004;96(1):P11-8. [14752239]
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