Stephen J. Schueler, M.D.

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Immune Thrombocytopenic Purpura Underlying Cause

The cause for idiopathic thrombocytopenic purpura is unknown. For some reason, the immune system, which normally fights infection, mistakenly attacks normal platelets in the bloodstream. This destroys platelets, which leads to abnormal bleeding. ITP seems to be triggered by viral infections.

Triggers include:

Continue to Immune Thrombocytopenic Purpura Types

Last Updated: Feb 3, 2011 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Immune Thrombocytopenic Purpura References
  1. Gibson M, Sehon JK, White S, Zibari GB, Johnson LW. Splenectomy for idiopathic thrombocytopenic purpura: a five-year retrospective review. Am Surg. 2000 Oct;66(10):952-4; discussion 955. [11261623]
  2. Kojouri K, George JN. Recent advances in the treatment of chronic refractory immune thrombocytopenic purpura. Int J Hematol. 2005 Feb;81(2):119-25. [15765779]
  3. Sandler SG. Review: immune thrombocytopenic purpura: an update for immunohematologists. Immunohematol. 2004;20(2):112-7. [15373659]
  4. Vesely SK, Perdue JJ, Rizvi MA, Terrell DR, George JN. Management of adult patients with persistent idiopathic thrombocytopenic purpura following splenectomy: a systematic review. Ann Intern Med. 2004 Jan 20;140(2):112-20. [14734334]
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