The evaluation of hypopituitarism begins with a history and physical examination.

Physical findings in someone with hypopituitarism may include:

• Short stature
• Failure of development during puberty

Tests that may be used to evaluate hypopituitarism include:

• Arginine test
• FSH level
• Growth hormone level
• Serum cortisol
• Serum estradiol
• Testosterone level
• Thyroid profile
• TSH level
• Urine 17-ketosteroids

Imaging tests that may be used to evaluate hypopituitarism include:

• CT scan of the brain
• MRI scan of the brain