To better understand Addison's disease, it helps to understand the anatomy of the pituitary and adrenal glands.
The adrenal glands are two triangular shaped endocrine glands located at the upper portion of each kidney.
The adrenal gland is composed of the adrenal cortex and the adrenal medulla.
The adrenal glands are stimulated by the pituitary gland, which is located in the lower, center portion of the brain.
Continue to Hypoadrenalism Physiology
- Baker JT. Adrenal disorders. A primary care approach. Lippincotts Prim Care Pract. 1997 Nov-Dec;1(5):527-36. 
- Don-Wauchope AC, Toft AD. Diagnosis and management of Addison's disease. Practitioner. 2000 Sep;244(1614):794-9. 
- Lin L, Achermann JC. The adrenal. Horm Res. 2004;62 Suppl 3:22-9. 
- Marzotti S, Falorni A. Addison's disease. Autoimmunity. 2004 Jun;37(4):333-6. 
- Perry CG, Connell JM. Key developments in endocrinology. Practitioner. 2003 Jul;247(1648):555, 558, 562.