Hypersecretion of Gastrin Underlying Cause
Zollinger-Ellison syndrome is caused by a tumor in the pancreas or stomach, called a gastrinoma. Gastrinomas may be cancerous or non-cancerous. Gastrinomas stimulate stomach cells to produce acid constantly. The over-production of stomach acid results in the symptoms of Zollinger-Ellison syndrome.
The cause for gastrinoma is unknown, but genetics may play a role. Benign tumors can interfere with body functions, but do not spread to distant areas of the body. Malignant, or cancerous, tumors invade or destroy normal body tissue. Their cells break away from the original tumor and spread to other parts of the body.
Continue to Hypersecretion of Gastrin Anatomy
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