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Hodgkin's Lymphoma Staging
- The type of cells that are multiplying in the lymph nodes
- Whether the lymphoma has spread to other lymph nodes or other organs
Most people with lymphoma are staged using the Ann Arbor system. This includes stages 1-4 (I-IV), along with certain letters that represent other factors.
The letter system includes:
- A: no symptoms
- B: symptoms of fever, night sweats or weight loss
- E:spread to one site nearby, but outside of affected lymph nodes
- X: bulky disease larger than 10 cm
In stage 1 (I), the lymphoma is present only in a single site, such as a lymph node.
In stage 2 (II), the lymphoma is present in 2 or more lymph nodes on the same side of the diaphragm, or in a single organ outside of the lymph nodes.
In stage 3 (III), the lymphoma is present on both sides of the diaphragm, with or without involvement of the spleen or other organs.
In stage 4 (IV), the lymphoma is present in multiple organs.
Continue to Hodgkin's Lymphoma Stage 1
PubMed Hodgkin's Lymphoma References
- Cartwright RA, Watkins G. Epidemiology of Hodgkin's disease: a review. Hematol Oncol. 2004 Mar;22(1):11-26. 
- Dieckmann K, Potter R, Wagner W, Prott FJ, Hornig-Franz I, Rath B, Schellong G. Up-front centralized data review and individualized treatment proposals in a multicenter pediatric Hodgkin's disease trial with 71 participating hospitals: the experience of the German-Austrian pediatric multicenter trial DAL-HD-90. Radiother Oncol. 2002 Feb;62(2):191-200. 
- McCunney RJ. Hodgkin's disease, work, and the environment. A review. J Occup Environ Med. 1999 Jan;41(1):36-46. 
- Provencio M, Espana P, Millan I, Yebra M, Sanchez AC, de la Torre A, Bonilla F, Regueiro CA, de Letona JM. Prognostic factors in Hodgkin's disease. Leuk Lymphoma. 2004 Jun;45(6):1133-9.