Stephen J. Schueler, M.D.

Hodgkin's Disease Overview

What is Hodgkin's disease?
A person with Hodgkin's disease has abnormal cells in the lymph nodes or spleen that multiply out of control. These cells can form tumors and spread to other parts of the body. Hodgkin's disease is most common in children and young adults, between the ages of 15 and 40. With early treatment, about 50 percent of those with Hodgkin's lymphoma can be completely cured. The two main types of lymphoma are Hodgkin's disease and non-Hodgkin lymphoma. The cause for Hodgkin's disease is unknown, but genes may play a role in determining risk.

What are the symptoms of Hodgkin's disease?
Initial symptoms of Hodgkin's disease include fatigue, fever, runny nose, sore throat, cough, and lymph node swelling in the neck, groin, and under the arms. Additional symptoms of Hodgkin's disease include excessive sweating, night sweats, chest pain, abdominal pain, pale skin, weight loss, and frequent upper respiratory infections.

How does the doctor treat Hodgkin's disease?
Treatment for Hodgkin's disease may include chemotherapy, radiation therapy, and surgical removal of the spleen.

Continue to Hodgkin's Disease Incidence

Last Updated: Feb 9, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Hodgkin's Disease References
  1. Cartwright RA, Watkins G. Epidemiology of Hodgkin's disease: a review. Hematol Oncol. 2004 Mar;22(1):11-26. [15152367]
  2. Dieckmann K, Potter R, Wagner W, Prott FJ, Hornig-Franz I, Rath B, Schellong G. Up-front centralized data review and individualized treatment proposals in a multicenter pediatric Hodgkin's disease trial with 71 participating hospitals: the experience of the German-Austrian pediatric multicenter trial DAL-HD-90. Radiother Oncol. 2002 Feb;62(2):191-200. [11937246]
  3. McCunney RJ. Hodgkin's disease, work, and the environment. A review. J Occup Environ Med. 1999 Jan;41(1):36-46. [9924719]
  4. Provencio M, Espana P, Millan I, Yebra M, Sanchez AC, de la Torre A, Bonilla F, Regueiro CA, de Letona JM. Prognostic factors in Hodgkin's disease. Leuk Lymphoma. 2004 Jun;45(6):1133-9. [15359992]
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