Hirschsprung's Disease Underlying Cause
Facts about congenital megacolon:
- Congenital megacolon is usually the result of absent nerves within the colon that normally control contraction of the colon. This condition is called Hirschsprung disease.
- Congenital megacolon is usually inherited.
- It is sometimes associated with Down's syndrome.
- Males are affected more frequently than females.
Continue to Hirschsprung's Disease Anatomy
- De Lorijn F, Reitsma JB, Voskuijl WP, Aronson DC, Ten Kate FJ, Smets AM, Taminiau JA, Benninga MA. Diagnosis of Hirschsprung's disease: a prospective, comparative accuracy study of common tests. J Pediatr. 2005 Jun;146(6):787-92. 
- Pena A, Levitt MA. Colonic inertia disorders in pediatrics. Curr Probl Surg. 2002 Jul;39(7):666-730. 
- Swenson O. Hirschsprung's disease: a review. Pediatrics. 2002 May;109(5):914-8. 
- Tomita R, Ikeda T, Fujisaki S, Tanjoh K, Munakata K. Hirschsprung's disease and its allied disorders in adults' histological and clinical studies. Hepatogastroenterology. 2003 Jul-Aug;50(52):1050-3.