Overview
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Underlying Cause
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Herpes Genitalis Pain Control
Medications commonly used to control pain and inflammation in adults with herpes genitalis include: ![]()
- Acetaminophen

- Controls pain, but has no anti-inflammatory properties
- Nonsteroidal anti-inflammatory drugs:
- Narcotic pain medications:

- Require a doctor's prescription
- Generally reserved for moderate to severe pain or severe pain
Acetaminophen
- Acetaminophen decreases fever and pain, but does not help inflammation.
- Adult dosing is 2 regular strength (325 mg) every 4 hours or 2 extra-strength (500 mg) every 6 hours.
- Maximum dose is 4,000 mg per day.
- Avoid this drug if you have alcoholism, liver disease or an allergy to the drug. See the package instructions.
- Common brand names include Tylenol, Panadol, and many others.
Aspirin
- Aspirin decreases pain, fever and inflammation.
- It is a nonsteroidal anti-inflammatory medication (NSAID).
- Adult dosing is two regular strength (325 mg) every 4 hours with food.
- There are numerous products that contain aspirin.
- Follow the package instructions and NSAID precautions (below).
Ibuprofen
- Ibuprofen decreases pain, fever and inflammation.
- It is a nonsteroidal anti-inflammatory medication (NSAID).
- Adult dosing is 200-400 mg every 4-6 hours.
- Do not exceed 1,200 mg per day without a doctor's recommendation.
- Brand names include Advil, Motrin and Nuprin.
- Follow the package instructions and NSAID precautions (below).
Naproxen
- Naproxen decreases pain, fever and inflammation.
- It is a nonsteroidal anti-inflammatory medication (NSAID).
- Adult dosing is 200 or 220 mg twice a day with food.
- Do not exceed 500 mg per day.
- Its brand name is Aleve.
- Follow the package instructions and NSAID precautions (below).
Ketoprofen
- Ketoprofen decreases pain, fever and inflammation.
- It is a nonsteroidal anti-inflammatory medication (NSAID).
- Adult dosing is 12.5 mg every 4-6 hours with food.
- Do not exceed 75 mg per day.
- Its brand name is Orudis KT.
- Follow the package instructions and NSAID precautions (below).
NSAID Precautions
- Avoid using alcohol when taking any of these medications.
- Do not mix prescription and non-prescription NSAIDS unless directed to do so by your doctor.
- NSAIDS can interact with other blood thinners, such as Coumadin, and cause bleeding complications.
- Ask your doctor before using an NSAID if you are pregnant or breastfeeding.
- Ask your doctor before using an NSAID if you have a history of:
Continue to Herpes Genitalis Warning Signs
Last Updated: Dec 15, 2010 References
Authors: Stephen J. Schueler, MD; John H. Beckett, MD; D. Scott Gettings, MD
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PubMed Herpes Genitalis References
- Corey L, Ashley R; Valaciclovir HSV Transmission Study Group. Prevention of herpes simplex virus type 2 transmission with antiviral therapy. Herpes. 2004 Aug;11 Suppl 3:170A-174A. [15319087]
- Spruance SL, Tyring SK, DeGregorio B, Miller C, Beutner K. A large-scale, placebo-controlled, dose-ranging trial of peroral valaciclovir for episodic treatment of recurrent herpes genitalis. Valaciclovir HSV Study Group. Arch Intern Med. 1996 Aug 12-26;156(15):1729-35. [8694673]
- Weiss H. Epidemiology of herpes simplex virus type 2 infection in the developing world. Herpes. 2004 Apr;11 Suppl 1:24A-35A. [15115627]