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Definition


Hemophilia A Definition
Common names:
  • Factor 8 Deficiency
  • Hemophilia A
What is hemophilia A?
Hemophilia A is an inherited bleeding disorder that only occurs in males. A male with hemophilia A is missing a protein called factor 8, which helps form blood clots. Normal blood coagulation requires the complex interaction of about 20 proteins, called clotting factors. Low levels of factor 8 result in prolonged blood clotting. Images

What are the symptoms of hemophilia A?
Symptoms of hemophilia A include prolonged bleeding, bleeding into the joints, joint swelling, joint pains, knee pain, bleeding gums, fatigue, nose bleeding, excessive bruising, blood in the stool, black stool, and a rash that looks like bruises or broken blood vessels. Images

How does the doctor treat hemophilia A?
Treatment for hemophilia A includes intravenous infusions of factor 8, fresh frozen plasma, desmopressin, and gene therapy. Images

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Last Updated: Mar 31, 2009  References
Authors: Stephen J. Schueler, MDJohn H. Beckett, MDD. Scott Gettings, MD
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